The title of the show is inspired by the classic medical textbook Gray's Anatomy. The series revolves around Dr. Meredith Grey, played by Ellen Pompeo, who began the show as a surgical intern at Seattle Grace Hospital in Seattle, Washington. Meredith Grey, a surgical resident, is the title character of the series Grey's Anatomy; her name is a reference to Henry Gray, the original author of the textbook Gray's Anatomy. Printed under the current title, "Henry Gray's Anatomy of the Human Body", as the 40th British edition in September 2008, the textbook on human anatomy has become a classic in medical schools, since first being published in 1858.The characters of the series include a group of surgical interns and the various physicians who serve as mentors to the interns in their professional and personal lives.